• Correlating Cardiac Structure to Function Using Nanoscale Resolution Scanning Ion Conductance Microscopy 

  Anamika Bhargava (Springer, 2022)

  Nanoscale resolution scanning ion conductance microscopy (SICM) is now at the forefront of imaging topography of biological cells even if they have complex and delicate surface structures. SICM offers several advantages ...
• Bacterial Outer Membrane Polysaccharide Export (OPX) Proteins Occupy Three Structural Classes with Selective beta-Barrel Porin Requirements for Polymer Secretion 

  Gaurav Sharma (AMER SOC MICROBIOLOGY, 2022)

  Diverse bacteria assemble and secrete polysaccharides that alter their physiologies through modulation of motility, biofilm formation, and host immune system evasion. Most such pathways require outer membrane (OM) ...
• Devising methodologies for sequence-based characterization of pathogens of global concern and development of web tools for biomacromolecular modeling and validation 

  L. Panoop Prasad Patro; Rathinavelan Thenmalarchelvi (Indian Institute of Technology , Hyderabad, 2022)

  The evolution of the field of bioinformatics, which harnesses biology, computer science, statistics, chemistry, physics and mathematics, has an enormous role in bridging the gap between biological bigdata and life. ...
• Phosphodiesterase structure-based design of pentoxifylline analogues, and computational and biochemical evaluation of pentoxifylline analogues and xanthine derivatives against phosphodiesterases functioning in sperm 

  Satish Mutyala; Rajakumara Eerappa (Indian Institute of Technology , Hyderabad, 2022)

  Phosphodiesterase (PDE) inhibitors, such as pentoxyfylline (PTX), are used as pharmacological agents to enhance sperm motility in assisted reproductive technology (ART), mainly to aid the selection of viable sperm in ...
• Mechanistic insights into allosteric regulation of methylated DNA and histone H3 recognition by SRA and SET domains of SUVH5 and the basis for di-methylation of lysine residue 

  Rajakumara Eerappa (Wiley, 2022)

  Su-(var)3-9 homologue 5 (SUVH5), a member of SUVH family of histone lysine methyltransferase (HKMT) in Arabidopsis, is involved in epigenetic regulation of chromatin by recognizing 5-methyl-cytosine (5mC), in both CpG and ...
• Erratum: Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure (mSystems (2021) 6:5 (e00095-21) DOI: 10.1128/mSystems.00095-21) 

  Sandipan Ray (American Society for Microbiology, 2022)

  Volume 6, no. 5, e00095-21, 2021, https://doi.org/10.1128/mSystems.00095-21. The author byline and affiliations should appear as shown in this correction. Page 3: The following should be added to the Fig. 1 legend. ‘This ...
• Isoform-specific expression of T-type voltage-gated calcium channels and estrogen receptors in breast cancer reveals specific isoforms that may be potential targets 

  Rahul Kumar; Anamika Bhargava (Elsevier B.V., 2022)

  Purpose: T-type voltage-gated calcium channels (TTCCs) have been implicated as novel targets in breast cancer treatment; however, the knowledge of isoform-specific expression of TTCCs in the pathology of breast cancer ...
• Emerging innovations for sustainable production of bioethanol and other mercantile products from circular economy perspective 

  Althuri Avanthi (Elsevier Ltd, 2022)

  Biogenic municipal solid waste (BMSW) and food waste (FW) with high energy density are ready to tap renewable resources for industrial scale ethanol refinery foreseen for establishing bio-based society. Circular economy ...
• Minichromosome maintenance proteins in eukaryotic chromosome segregation 

  Gunjan Mehta; Rajakumara Eerappa (John Wiley and Sons Inc, 2022)

  Minichromosome maintenance (Mcm) proteins are well-known for their functions in DNA replication. However, their roles in chromosome segregation are yet to be reviewed in detail. Following the discovery in 1984, a group of ...
• Interactions between HIV protease inhibitor ritonavir and human DNA repair enzyme ALKBH2: a molecular dynamics simulation study 

  Anindya Roy (Springer Science and Business Media Deutschland GmbH, 2022)

  The human DNA repair enzyme AlkB homologue-2 (ALKBH2) repairs methyl adducts from genomic DNA. Overexpression of ALKBH2 has been implicated in both tumorigenesis and chemotherapy resistance in some cancers, including ...
• Geographical distribution of SARS-CoV-2 amino acids mutations and the concomitant evolution of seven distinct clades in non-human hosts 

  Rathinavelan Thenmalarchelvi (John Wiley and Sons Inc, 2022)

  Since its first emergence in December 2019, the world has witnessed the eruption of mutations in the SARS-CoV-2 genome that have led to increased viral transmissibility and pathogenicity due to sustained local viral ...
• Computational, biochemical and ex vivo evaluation of xanthine derivatives against phosphodiesterases to enhance the sperm motility 

  Rajakumara Eerappa (Taylor and Francis Ltd., 2022)

  Enhancing sperm motility in vitro has immensely benefited assisted conception methods. Phosphodiesterases (PDE) break the second messenger cAMP, and therefore, inhibition of their catalytic activity enhances the sperm ...
• Pro- and anti-inflammatory bioactive lipids imbalance contributes to the pathobiology of autoimmune diseases 

  Undurti N. Das (Springer Nature, 2022)

  Autoimmune diseases are driven by TH17 cells that secrete pro-inflammatory cytokines, especially IL-17. Under normal physiological conditions, autoreactive T cells are suppressed by TGF-β and IL-10 secreted by microglia ...
• Silver sulfadiazine loaded core-shell airbrushed nanofibers for burn wound healing application 

  Rajakumara Eerappa; Jyotsnendu Giri (Elsevier B.V., 2022)

  Ideal dressing materials for complex and large asymmetric burns should have the dual properties of anti-bacterial and regenerative with advanced applicability of direct deposit on the wound at the patient bedside. In this ...
• Structure and Cooperativity in Substrate-Enzyme Interactions: Perspectives on Enzyme Engineering and Inhibitor Design 

  Rajakumara Eerappa (American Chemical Society, 2022)

  Enzyme-based synthetic chemistry provides a green way to synthesize industrially important chemical scaffolds and provides incomparable substrate specificity and unmatched stereo-, regio-, and chemoselective product ...
• Editorial: Early Detection and Diagnosis of Cancer 

  Rahul Kumar (Frontiers Media S.A., 2022)

  Abstract is not Available.
• Beneficial Actions of Essential Fatty Acids in Streptozotocin-Induced Type 1 Diabetes Mellitus 

  Undurti N. Das (Frontiers Media S.A., 2022)

  The essential fatty acids (EFA), n3 alpha-linolenic acid (ALA), and n6 linoleic acid (LA) are of benefit in diabetes mellitus, but their mechanisms of action are unknown. We, therefore, examined the effects of EFAs on the ...
• STRIDER: Steric hindrance and metal coordination identifier 

  Rathinavelan Thenmalarchelvi (Elsevier Ltd, 2022)

  Biomolecular structural knowledge is important to understand the biological processes and the mechanisms underlying human diseases. In silico modeling plays a vital role in de novo design and docking of biomacromolecules ...
• Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study 

  Undurti N. Das (MDPI, 2022)

  Radiation is pro-inflammatory in nature in view of its ability to induce the generation of reactive oxygen species (ROS), cytokines, chemokines, and growth factors with associated inflammatory cells. Cells are efficient ...
• Solvent controlled synthesis of 2,3-diarylepoxy indenones and α-hydroxy diarylindanones and their evaluation as inhibitors of DNA alkylation repair 

  Anindya Roy; Faiz Ahmed Khan (Royal Society of Chemistry, 2022)

  Herein, we report a novel and unexpected metal-free oxygenation of 2,3-diphenyl-1-indenones, under an oxygen atmosphere (air), to either 2,3-epoxy-2,3-diphenyl-1-indenone or 2-hydroxy-2,3-diphenyl-1-indanone, depending on ...

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